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How Is Immunotherapy Changing Cancer Treatment?

immunotherapy for cancer treatment

What is immunotherapy?

Immunotherapy or immuno-oncology is a type of cancer treatment that uses the power of the body’s own immune system to treat cancer by either controlling, preventing or eliminating cancer. The role of immunotherapy in cancer is to boost the immune cells to overpower and eliminate cancer cells. It educates the immune system on targeting specific cancer cells and provides the body with additional integrants to enhance its immune response.

Immunotherapy for cancer treatment comes in a variety of forms. It includes targeted antibodies, cancer vaccines, tumour-infecting viruses, adoptive cell transfer, cytokines and adjuvant therapy.

Immunotherapy is interchangeably used with biological therapy. Because they use elements from living organisms to fight disease, immunotherapies are a type of biotherapy (also known as biologic therapy or biological response modifier (BRM) therapy.) Gene therapies are immunotherapy treatments that use genetic engineering to improve immune cells’ cancer-fighting capabilities. Many immunotherapy treatments for cancer prevention, management, or treatment can be combined with surgery, chemotherapy, radiation, or targeted therapies to boost their efficacy.

Which Cancers Are Treated With Immunotherapy?

Immunotherapy is suggested on a case-by-case basis to see if it is right and beneficial for each patient. Immunotherapy has proven to be a promising therapeutic option for a variety of cancers, including breast cancer, bladder cancer, cervical cancer, colorectal cancer, leukemia, liver cancer, lung cancer, multiple myeloma, prostate cancer and many others.

Immunotherapies can be injected into a vein, injected into a muscle, injected under the skin (subcutaneously). Certain types of immunotherapy can be administered directly to the tumour’s location in the bodily cavity.

What is immunotherapy cost in India?

Immunotherapy treatment intended for cancer patients stimulates the immune system of the body to battle the cells of cancer. Immunotherapy started a few years ago and advances every day in India. There are numerous immunotherapy sessions within one month depending on the patient’s conditions ( subjective to patients). The expense for a session varies from 1-1.5 lakh INR. Doctors plan therapy hours and prescription levels according to the professional assessment of the patient and further necessities.

Cancerrounds is committed to delivering the best immunotherapy treatment at the best cost so that our patients can benefit from them. Additionally, our multispecialty team of professionals provides excellent clinical care for immunotherapy patients, regularly assessing their responses to treatment and changing their treatment regimens as appropriate. For appointments or queries, visit www. cancerrounds.com

Posted by, magneto
February 21, 2022
breast cancer

ONCOPLASTIC BREAST SURGERY OR THE PERSPECTIVES FOR BREAST-CONSERVATION SURGERY (BCS)

Breast-conservation surgery (BCS) and Oncoplastic breast surgery is a safe option for most female with early breast cancer.  

Yes, its recently, innovations in stream of oncoplastic techniques that have aided the cancer patients with reduced surgical trauma and a conservative approach that again is capable of preserving the breast. 

In spite of the most apt managing options of primary closure, the oncoplastic breast surgery or BCS defects are encountered with the aesthetic outcome – that may be unpredictable.  

In this lieu the oncology team of patient approaches the arm of Oncoplastic reconstruction. The oncoplastic reconstruction can itself be begin at the time of BCS (immediate). Or oncoplastic surgery can also be followed by oncoplastic reconstitution that is done in weeks (delayed-immediate) or months to years afterwards (delayed).  

It is essential here to mention that in the cases where immediate reconstruction is done, the surgical process is smooth as the steps are associated in one operative setting.  

As per the data reported by best oncologists offering best breast cancer treatment in India enlist that the 5-year survival of BCS with radiation is not statistically different in contrast to mastectomy offered alone as conventional treatment in patients with Stage I or II breast cancer. 

Statistical scoops also alarm that about 10% to 30% of patients submitted to BCS are not satisfied with the aesthetic outcome that include the clinical aspects related to skin pigmentation changes, telangiectasia, and skin fibrosis. In the glandular tissue, local radiation causes fibrosis and retraction. 

Talking about the raising attention to oncoplastic procedures – that offers the immediate application of plastic breast surgery techniques that provide a wider local excision allows to achieve the goals of a better breast shape and symmetry  

It is well accepted that oncoplastic breast surgery referred as the modern oncoplastic breast surgery combines principles of oncologic and plastic surgery techniques. This combination of principles of oncology and plastic surgery allowed the doctors to obtain oncologic ally sound and aesthetically pleasing results.  

What the oncoplastic techniques are related to? – the oncoplastic technique are related to volume displacement or replacement procedures.  

Yes, oncoplastic approach can be started at the time of BCS (immediate), weeks (delayed-immediate) or months to years afterwards (delayed) as well. The main advantages of the technique utilized should include reproducibility and patient satisfaction.  

This surely includes the main goal of low interference with the oncologic treatment and long-term results.  

Another aspect of oncoplastic breast surgery being preferred is the possibility of accomplishing negative resection margin. As the immediate reconstruction allows for wider local tumor excision, potentially reducing the incidence of margin involvement and this idea emphasize on permitting larger resections, with a superior mean volume of the specimen and negative margins. 

Possibly an ideal procedure or recommended guidelines does not exist and each case should be planned individually. As any surgical technique, all these goals are probably not met by any single procedure as each case with individual technique presents particular advantages for their indications, tumor location limitations, vascular pedicle, additional skin and glandular resections due to compromised margins, and resultant scar.  

Clinical results of oncoplastic breast surgery- are better and we also cannot neglect that immediate BCS reconstruction is challenging for oncological and plastic surgeons. The data recently supports that the oncoplastic approach associated with BCS can be considered as safe as mastectomy in tumours less than 2 cm and possibly safer than the BCS.  Another important issue in limitations associated is related to the complication rates and the timing of reconstruction; as in BCS with delayed reconstruction complication rates have been shown to be higher than immediate reconstruction. 

For more details and second opinion on breast cancer treatment – please contact Cancer Rounds. 

Posted by, magneto
February 3, 2022

Bone Marrow Transplant (BMT) Specialist OR Hematopoietic Stem Cell Transplant Specialist! – What to Consider Wisely Before Choosing BMT SPECIALIST?

bone marrow treatment in india

In our bones, spongy tissue is presently termed bone marrow which is responsible for the formation of blood cells. Yes, all the blood cells are formed “hematopoietic stem cells” or simple “stem cells”.

The special characteristics of the hematopoietic stem cell help them to renew themselves. Besides this, hematopoietic stem cells or stem cells in none marrow also can develop into any type of blood cells.

“Hematopoietic stem cell transplantation or bone marrow transplantation” is the technique that aids the injection of stem cells from bone marrow that produce red blood cells, white blood cells, and platelets into a recipient after a short course of chemotherapy called conditioning.

Before the process of Hematopoietic stem cell transplantation or bone marrow transplantation, the process of filtering stem cells is done and the goal of BMT is to transfuse healthy bone marrow cells in patients.

Bone marrow transplant treatment is used successfully to treat diseases such as leukemias, lymphomas, aplastic anemia, immune deficiency disorders, multiple myeloma, etc

The different types of BMT include the following: Autologous bone marrow transplant in which the donor is the patient himself or herself. And the other is the Allogeneic bone marrow transplant in which the donor shares the same genetic type as the patient.

Matching involves typing human leukocyte antigen (HLA) tissue. The antigens on the surface of these special white blood cells determine the genetic makeup of a person’s immune system. There are at least 100 HLA antigens; however, it is believed that there are a few major antigens that determine whether a donor and recipient match. The others are considered “minor” and their effect on a successful transplant is not as well-defined.

After knowing briefly about the bone marrow transplant treatment, let us understand the role of the bone marrow transplant team:

The bone marrow transplant team is comprised of a group of specialists that work together for a successful transplant. The team consists of professionals specialized in oncology, hematology, immunology, and bone marrow transplantation. Besides this, the role of the bone marrow transplant nurse coordinator who organizes all aspects of care provided before and after the transplant can never be forgotten. As the bone marrow transplant nurse coordinator educates the patient, caregivers coordinate the diagnostic testing and are present for counseling during follow-up care.

Now comes the treasure where you can understand how wisely you can decide the appropriate right bone marrow transplant specialist in India.

It is necessary to take reference before approaching the specialist. In this, you can collect information from social media, digital platforms, your relatives, and your family doctor.

Besides this our virtual hospital Cancer Rounds also provides a second opinion as well to ambulatory or remote cases who are hunting the right bone marrow transplant specialist to proceed with.

Cancer Rounds is impregnated with the leading and the best cancer doctor in India, with the boon of both expertise and experience – here we also avail our patients to get their comments about those doctors before interacting with them. Once you are satisfied proceed to read reviews of patient survivors’ stories available on the website that will surely answer your queries i.e. why the particular doctor is preferred for you.

Not always we meet positive comments and doctors are also human, in case you come across some negative comments about their doctor, always scrutinize the comment because each case is different. This will give you the idea if it is a wise decision to go for the concerned specialist of Bone Marrow Transplant.

The bone marrow transplant specialist team in Cancer Rounds has strong experience with a bone marrow transplant, as they are also updated to provide you with answers to queries like- what options do exist and how each one works for your situation.

The focus of Cancer Rounds is to reach far/remote patients as well, in this, we are guiding accommodation, financial aids as well because the first thing you come across during treatment is that it’s not possible for patients during different phases of treatment to travel far away.

The success in a bone marrow transplant procedure is the cure of disease that is not achieved instantly.

Bone marrow transplant treatment is life-saving and in India the cost for BMT treatment range from about Rs. 15, 00,000 to 40, 00,000.

You can also contact us directly, in case require a second opinion for a Bone marrow transplant for yourself or your loved being.

Posted by, Medical Team, Cancer Rounds
January 25, 2022
Why can a second opinion in cancer be helpful?

Why can a second opinion in cancer be helpful?

Cancer is a dangerous disease and the proper diagnosis will help you with a comfortable and confident recovery plan. When you’re taking treatment for cancer, it’s obvious to have thoughts if another doctor can offer more information or another treatment option that will be more beneficial. You may want to find another doctor to look at your test results, speak to you about your personal situation, and maybe give you another perspective on it. Getting a second opinion in cancer can help validate the first doctor’s view or offer advice on potential treatment choices. It will make you feel more positive about your care plan and diagnosis.Why can a second opinion in cancer be helpful? Let’s find out –

Some Facts and Figures:

  • The prevalence of cancer in India is estimated at around 2.5 million, with around 1.25 million new cases reported each year and around 800,000 deaths due to the disease.
  • The second opinion is a patient’s method of finding an alternative assessment of his or her diagnosis and treatment plan by another, or by a few other specialist doctors to confirm the diagnosis and validate their treatment.
  • Before treatment, many patients seek a second opinion for confirmation or diagnosis for a complex condition. Researchers say that as many as 88 per cent of those patients go home with a new or advanced diagnosis — changing their treatment plan and possibly their lives. In contrast, only 12 per cent receive confirmation that the original diagnosis was correct and complete.
  • Few studies have shown that up to 30 per cent of people seeking second advice found that their original treatment for recovery did not suit the substitute treatment, and the latter proved more effective in most cases. Although taking second opinions isn’t a new concept, it has gained popularity in recent times as a medical service. It is quite common for patients to seek a second opinion, in particular for life-threatening diseases such as cancer.

Why can a second opinion in cancer be helpful?

You should not worry and feel free to ask your doctor for a second opinion. It is not offensive and it is the right of the patient. Doctors are usually happy and help their patients arrange a second opinion. Your doctor wants the best treatment approach for your cancer and a second opinion will help him plan treatment for a confirmed diagnosis.

You should consider seeking a second opinion when:

  • A rare form of cancer has been diagnosed.
  • Your doctor has little experience in treating your type of cancer.
  • You have several recovery choices, so you remain confused about what to do.
  • Your test results are unclear regarding your cancer type and location.
  • A condition or recovery program doesn’t make you happy.

Even if you already had the treatment you can get a second opinion. A second opinion can make recommendations for how your treatment will progress.

How a Second Opinion Can Help:

Why can a second opinion in cancer be helpful? Patients diagnosed with cancer often experience a wide spectrum of feelings, as well as a feeling of desperation to start treatment as soon as possible. Typically there is a period of time for a new diagnosis, based on the form and severity of the disease before the therapy starts. Obtaining a second opinion at this period may be an important and appropriate part of treating one’s condition. It can contribute to:

  • Approve your diagnosis.
  • Determine if cancer is spreading.
  • Viewpoint from experts with different expertise (such as a radiation oncologist or surgical oncologist)
  • Determine clinical trials or alternative treatments that apply to your treatment plan
  • Other medications.
  • Imbibe confidence on how to proceed with your care.

Is there time to wait for a second opinion?

Treatment plans are to be made after you have a clear picture of your diagnosis and learned all you can about your prognosis, and the treatment options available. Depending on the type of cancer you have, it may take time. In some cancers, few treatment decisions have to be made right away. It is completely acceptable if you take some time to think about them, and you should think about them. If you are worried about the delay at the start of treatment, you should talk to your doctor.

Second opinion etiquette:

You may be concerned that if you decide to seek advice from another health care professional, your doctor will be offended, but most doctors understand that many patients decide to seek a different opinion, and will want you to feel comfortable and secure before starting treatment.

Honestly, it is an integral part of the bond between doctor and patient, and experts suggest that you make your doctors aware of your decisions. You’ll need to collect medical records from your original appointment, and this may be a time to let your doctor know you’re exploring other treatment options.

How to get started seeking a second opinion?

Talk to your doctor:

First, tell your doctor you want to get a second opinion. Patients with cancer typically request a second opinion, and certain insurance programs also require one, particularly if a doctor suggests surgery or alternative therapy.

Some individuals may not feel comfortable talking to their doctor about getting a different opinion. To make it easier to discuss the issue, tell your doctor that you are satisfied with his or her treatment plan and care, but that you want to ensure that you are fully informed about all the treatment options available. When you have the conversation, it may help to bring a family member or friend along for support.

Get copies of your medical records:

Tell the doctor for the medical history, original X-rays, examination, and test reports and you can take them with you for a second opinion on your first appointment. You may also send the information from the current doctor from the new doctor’s office if that is more convenient. Many hospitals allow patients access to their own medical records.

It is a good idea to ask your medical records even if, in case of an emergency, you don’t want to seek a second opinion.

Timing:

It should not take longer than a week for a cancer specialist office to collect information from your previous doctor’s office and book a second opinion consultation for you. If you plan to bring your medical records to the appointment, it may take even less time than to ask your primary doctor to forward them.

When you have to wait for a second opinion for longer than a week or two to see a doctor, you may want to find someone else.

Here are a few reasons to consider a Second Opinion

Here are five reasons why getting a second opinion should be a top priority on the path to recovery:

  • Peace Of Mind

A cancer diagnosis is disturbing, and even if you feel like you’ve already found the right team, you may want reassurance to quell the ‘what-ifs.’ Sometimes a second opinion is important not because you’re going to be diagnosed with something else, but just to confirm what the initial consultation team has already said. That brings trust and confidence in the treatment.

  • Up-To-Date Treatment And Technology

The knowledge about cancer and how to treat it is changing fast. Every year, new researches provide insight that can lead to more adequate treatment, and although oncologists may occasionally seem like super-intelligent superheroes, they are humans and there’s always a welcoming open door of learning new things.

  • Different Perspectives

Most of the time, a team of experts is responsible for a successful treatment and not just one doctor’s efforts. It requires a team of oncologists, surgeons, and more who each bring a different perspective and approach to treatment.

  • Access To Clinical Trials

Clinical trials, the real-world research studies involving people allow oncologists to determine new approaches in limiting, diagnosing, and tackling diseases. Most of the time, cancer patients who seek second opinions at different setups will learn of a current or upcoming clinical trial that’s right for them or their treatment plan.

If You are not satisfied with what you heard. If you’re filled with fear and doubt after your first opinion, then you should know that another doctor may have a different approach. And just because one doctor indicates an alarming prognosis, there might be another doctor offering more hope.

What if the Second Opinion doesn’t match with the First?

There are pretty good chances that the second opinion will be similar to that of your first doctor. So if that is the case you can feel more confident in your diagnosis and treatment plan.

However, the second doctor may have different ideas about diagnosis or treatment. If that happens, DO NOT worry — you still have choices. You should go back to the first doctor to address the second opinion. You can agree together to adjust your treatment based on this new knowledge. You should get a third doctor’s opinion, too. It could help you decide which of your first two choices is better.

Remember you don’t have to switch doctors even if you get a second or third opinion. You’ll be able to decide which doctor will do your treatment.

Now, why can a second opinion in cancer treatment be helpful?

When a patient walks in for their initial consultation after a cancer diagnosis, they bring a plethora of problems in their mind. Typically they come to get detailed information about their condition after they have already been given a diagnosis of cancer. They arrive at an oncology clinic in a state of panic and disturbance. They also have questions about their future life and how normal it will be. Typically when getting a second opinion, consultation is via a follow-up call following a biopsy and/or examination to confirm that they have cancer. Receiving a similar diagnosis produces a strong emotional reaction.

Most cancer cases are usually clear and straightforward. A clear diagnosis is made and treatments are initiated. In such cases, many patients may not need a second opinion. But when a diagnosis of a unique cancer is made, there is much fear, misconceptions, and many questions about treatment. All these factors can determine whether a person may live or die, thus it is not totally acceptable to a patient to want to have another point of view-what we call a second opinion.

The most valuable thing a doctor can provide to a patient or family concerned after reviewing the cancer data is to explain, in clear terms, all the related issues. Patients want state-of-the-art medical treatment but may have reservations about what is the right way to go about it. Although this is when a second opinion can be very helpful in doing so, most patients are reluctant to offend their primary doctor. Many patients may not know it’s a common procedure to have a second opinion.

It is really important for the patient and his family/friends to give themselves time to know exactly what the diagnosis means unless emergency care is required. They need to gather information on how to treat it (surgery, radiation, or chemotherapy), weigh the options (if immediate treatment has an effect on their particular disease), and understand the prognosis and chances of a cure.

Conclusion

Having a second opinion can help you determine the cancer treatment tailored to meet your needs. Many factors determine how long a second opinion evaluation takes. During the diagnosis, a dedicated team of oncologists, nurses, dietitians, and other cancer specialist collaborate with you to assess your medical history, diagnostic tests, and treatment status. They may also use additional diagnostic technology to further evaluate the disease. Using all this information, they plan your personalized treatment plan. If you are looking for a cancer consultant, then Cancer Rounds is the best place to book an appointment. Cancer Rounds can help you connect with the best Cancer hospital in India. Visit Cancer Rounds’ website today.

For more such information, You can also read:

Cancer and Mental Health

Treatment of Lung Cancer by Surgery

Posted by, Medical Team, Cancer Rounds
July 15, 2020

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