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15 Feb : International Childhood Cancer Day

International Childhood Cancer Day

15th of February is International Childhood Cancer Day. It is celebrated globally to raise awareness about childhood cancer, express gratitude and support for children, cancer survivors and families. Every year, more than 4 lakh children and adolescents under the age of 20 are diagnosed with cancer. In India, around 50,000 children are diagnosed with cancer each year, or one child every 11 minutes. Early detection and specialized, precise treatment is an indispensable solution to fighting this disease.

 

Cancer Rounds celebrates this day to show immense support, compassion and offer help to children and their families suffering from this dreaded disease.

 

Symptoms: Some generalized symptoms of cancer in children include unusual swelling, pallor in the child (pale appearance), loss of appetite, loss of weight, etc. Early detection of the cancer is the key to preventing cancer from worsening.

 

Following are the most common cancers seen in children.

  • Leukemia: The most prevalent childhood cancer is leukemia, which is a disease of the bone marrow and blood. They account for roughly 28% of all childhood malignancies. Acute lymphocytic leukemia (ALL) and acute myeloid leukemia (AML) are the most frequent forms in children

 

  • Brain and spinal cord tumors: These are the second most frequently occurring cancer in children, accounting for around 26% of all cancers in this age group. There are different types of brain and spinal cord cancers, each with its own treatment and prognosis.

 

  • Neuroblastoma: This type of cancer develops in the initial stages of nerve cells in a growing embryo or fetus. Neuroblastomas account for about 6% of all juvenile malignancies. This is a malignancy that affects newborns and young children. It is uncommon in children above the age of ten years.

 

  • Nephroblastoma (also known as Wilms tumor) is cancer that originates in one or both kidneys. It is most frequent in kids between the ages of 3 and 4, and it is uncommon in older children and adults.

 

  • Lymphoma (including both Hodgkin and non-Hodgkin): Lymphomas arise in immune system cells called lymphocytes. The lymph nodes or other lymph tissues, such as the tonsils or thymus, are the most common sites for these cancers to begin.

 

  • Bone cancer (includes osteosarcoma and Ewing sarcoma): Bone cancers (primary bone cancers) are most common in older children and teenagers, but they can develop at any age. They are responsible for around 3% of all childhood cancers.

 

  • Other less frequent childhood cancers include cancer of the skeletal muscles (Rhabdomyosarcoma) accounting for 3% of childhood cancers and cancer of the eyes (Retinoblastoma) accounting for 2% of the childhood cancers.

 

Cancer Rounds strikes to bring you the best cancer treatment from the best cancer hospital in Gurgaon and across India, help you connect with the best oncologist and provide a hassle-free experience. Let us all join hands and help the little hearts to fight cancer.

Posted by, magneto
February 15, 2022

Radiation Vs. Surgery For Cancer Treatment

Cancer, as we all know is the uncontrollable growth of cells that spreads to other body parts, cause organ failure or death. For the year 2020, India has had 1,392,179 cancer patients, with the breast, lung, mouth, cervix uteri, and tongue being the top five cancer sites. According to the Cancer Statistics Report, 2020, the projected incidence for men was 94.1 per 100,000 people, and for women, it was 103.6 per 100,000 people. In this article, two frequently used treatment options are explained in detail. They are cancer treatment by surgery and radiation therapy.

Cancer treatment by surgery:

Surgery is the most common approach to cancer treatment. It involves removing tumours or areas containing cancer cells. Most cancer patients are scared of this procedure, but doctors strongly advise it, especially if the cancer cells have not begun to multiply in the body. During surgery, the entire area where cancer cells are found is removed.

Surgical procedures are carried out either robotically or manually by the oncologists. Robotic surgery is more commonly used nowadays because it is easier and safer. The term “robotic surgery” refers to a procedure in which a machine enters the body and removes cancer cells. When compared to surgery performed by human hands, it has fewer side effects on the body. At Cancer Hospital in Gurgaon, doctors thoroughly assess the patient’s condition and try to use the best surgical method that cures the patient to the maximum. Treatment options are also determined by the patient’s condition.

Doctors prescribe medications to help the body part heal after surgery. Routine check-ups are also performed to avoid future complications. Depending on the situation, you may be advised to stay in bed and take a rest for a few months or weeks. Supportive care and rehabilitation services for your emotional well-being are also available if needed.

Cancer treatment by radiation therapy:

In India, radiation therapy is the second most popular and safe treatment option for cancer patients. Doctors use high-energy waves to destroy the cancer cells and prevent them from spreading to other parts of the body in this method.

Patients will not experience any of the pain that they would experience during surgery during the course of radiation therapy. However, after the therapy, they are seen to be suffering from pain, anxiety, fatigue, skin rashes, and a variety of other side effects. At centers of radiation therapy for cancer in India, doctors usually recommend radiation therapy when cancer is in its early stages. This method of treatment is most commonly used for children with cancer who are unable to bear the pain of surgery. But, if the condition is serious, doctors will choose the best treatment option after weighing the benefits and drawbacks of various options.

Surgery Vs. Radiation therapy: Which cancer treatment should I choose?

If you’re not sure which of these treatments is right for you, the best thing to do is leave it up to the doctors who are treating you. After considering various factors, they can select the best treatment method for you. If you’re still not convinced by your doctor’s recommendations, you can always seek a second opinion to see what works best for you.

Radiation and surgery both are extremely safe. When it comes to side effects, surgery is more likely to cause serious complications than radiation therapy. Depending on your health condition, your doctor may recommend a combination of treatments to help you recover as quickly as possible. Treatment at a cancer hospital with a multidisciplinary team of cancer care experts and oncologists who can provide an unbiased opinion is always preferable.

For more information about cancer treatments in India, visit our website www.cancerrounds.com. You can reach us with your queries at our toll-free customer care number.

Posted by, magneto
February 14, 2022

Myths And Facts About Breast Lumps And Cancer

Breast Cancer

 

Breast cancer is one of the most common cancers among Indian women, with a rate of 25.8 per 100,000 women and a mortality rate of 12.7 per 100,000 women.

Not only the numbers are increasing each day but also the myths and doubts about breast cancer. It is recommended to do a breast self-examination monthly in about 3 to 5 days after the period starts.

When you feel a lump in your breast or you experience any breast cancer symptoms, it’s understandable to be concerned. But don’t panic and jump to conclusions. Instead, act wisely and call your doctor to discuss.

 

Myths About Breast Cancer

Always make sure you are away from these popular 7 myths of breast cancer and know the facts.

 

Myth No. 1: A breast lump Is certainly cancer

Eight out of ten breast lumps felt by women aren’t cancer. A cyst (a sac) or a fibroadenoma (an abnormal growth that isn’t cancer) are the most common types. During a woman’s menstrual cycle, some lumps appear and disappear.

It’s impossible to tell what it is based on how it feels. You should consult a doctor to know in detail about the lump.

 

Myth No. 2: A single test can confirm breast cancer

More tests, such as an MRI, ultrasound, or a follow-up mammogram, may be required to examine the lump again.

A biopsy, in which a doctor takes a small sample of the lump to test it, may also be required. Regular examination is the ultimate key to detecting/preventing breast cancer.

 

Myth No. 3: Breast cancer lumps are always painless

Certainly not. Breast cancer isn’t always painful, and having breast pain doesn’t rule out the possibility of cancer.

When there is a lump, inflammatory breast cancer symptoms such as redness, swelling, tenderness, and warmth in the breast, can be painful.

 

Myth No. 4: You can’t have cancer if you find a lump while breastfeeding

Breastfeeding reduces your chances of getting breast cancer, but it can still happen. Don’t ignore a lump if you notice it while breastfeeding. Always discuss with your doctor and go for a suggestive diagnostic test.

 

Myth No. 5: A breast lump can’t be cancer if you’re young

That is not the case. Breast lumps should be self-examined every month as mentioned earlier about 3-5 days after the period starts at any age.

Even though the majority of women diagnosed with breast cancer are past menopause or over the age of 50 years, stats are rapidly changing and a lump in the breast can be cancerous in a younger woman too.

 

Myth No. 6:  A smaller size of the lump is less likely to be cancerous than a larger size lump

This is certainly not true. Breast lumps irrespective of the size should be discussed with the oncologist or the gynaecologist and should be considered for suggestive diagnostic tests.

At times, small lumps may progress to aggressive cancers and shouldn’t be ignored.

 

Myth No, 7: If you don’t have a family history of breast cancer, a lump is probably harmless

If no one in their family has had breast cancer, many women believe they aren’t at risk. That is not the case. According to the American Cancer Society, only about 15% of women with breast cancer have a relative who has had the disease.

Whether or not breast cancer runs in your family, have all lumps examined by a doctor.

 

For more informative content on various types of cancer, its diagnosis, queries and breast cancer treatment in India, send us a query or visit our website www.cancerrounds.com.

Posted by, magneto
February 9, 2022

Aplastic Anemia With Emphasis On The Treatment Options

Aplastic Anemia

Aplastic anemia occurs when human body stops producing enough new blood cells. The condition leaves the individual fatigued and more prone to infections and uncontrolled bleeding. Aplastic anemia can be short-lived, or it can become chronic. It can be severe and even fatal. It less common and serious condition, which can develop at any age. Aplastic anemia can occur suddenly, or it can come on slowly and worsen over time. Clinically presented as mild or severe.

Aplastic anemia can have no symptoms but if present, signs and symptoms can include:

1. Fatigue

2. Shortness of breath

3. Rapid or irregular heart rate

4. Pale skin

5. Frequent or prolonged infections

6. Unexplained or easy bruising

7. Nosebleeds and bleeding gums

8. Prolonged bleeding from cuts

9. Skin rash

10. Dizziness

11. Headache

12. Fever

The following tests can help diagnose aplastic anemia in the designed diagnostic workup for Aplastic anemia:

Blood tests include complete blood cell count – In aplastic anemia all three of these blood cell levels are low.

Bone marrow biopsy is done by a needle to remove a small sample of bone marrow from a large bone in your body, such as your hipbone. The sample is examined under a microscope to rule out other blood-related diseases. In aplastic anemia, bone marrow contains fewer blood cells than normal.

Treatment provided for aplastic anemia by Top hematologists in Gurgaon is dependent on the severity of condition and demographic details like age.

The treatment options include: observation, blood transfusions, medications, or bone marrow transplantation. Severe aplastic anemia, in which your blood cell counts are extremely low, is life-threatening and requires immediate hospitalization.

Blood transfusions: not cure for aplastic anemia, blood transfusions control bleeding and relieve symptoms by providing blood cells in patient’s bone marrow that isn’t producing. While there’s generally no limit to the number of blood transfusions but complications can sometimes arise with multiple transfusions.

Stem cell transplant: done to rebuild the bone marrow is considered to be the only successful treatment option for people with severe aplastic anemia. A stem cell transplant, also called a bone marrow transplant, is generally the treatment of choice in younger patients.

Immunosuppressants is preferred in cases who can’t undergo a bone marrow transplant or for those whose aplastic anemia is due to an autoimmune disorder. In this the treatment can involve drugs that alter or suppress the immune system (immunosuppressants). Drugs such as cyclosporine (Gengraf, Neoral, Sandimmune) and anti-thymocyte globulin suppress the activity of immune cells that are damaging bone marrow. This helps bone marrow recover and generate new blood cells. Corticosteroids, such as methylprednisolone (Medrol, Solu-Medrol), are often used with these drugs.

Bone marrow stimulants in verities that are including colony-stimulating factors, such as sargramostim (Leukine), filgrastim (Neupogen) and pegfilgrastim (Neulasta), epoetin alfa (Epogen/Procrit), and eltrombopag (Promacta). These drugs help stimulate the bone marrow to produce new blood cells

Antibiotics, antivirals are administered in cases of aplastic anemia. Because the condition has weakens]ed your immune system, which leaves you more prone to infections.

Other treatments for Aplastic anemia caused by radiation and chemotherapy treatments for cancer usually includes follow up observations as it improves after those treatments stop. The same is true for most other drugs that induce aplastic anemia.

For more details please contact Cancer Rounds

Posted by, magneto
February 1, 2022

Suspected for Diagnosis of Cancer – Identify The Symptoms Associated With It

Cancer is a most deadly and ironic diagnosis that is becoming one of the leading causes of increased mortality these days. Cancer can be successfully treated if it is identified at an early stage by symptoms of cancer and in certain cases can be cured.

The cancer treatment design also includes palliative care services to recover emotionally and this is of great help to cancer patients and survivors. The diagnostic workup done for early-stage diagnosis of suspected cancer cases include the screening steps and diagnosing the disease as early as possible is very important for a good prognosis.

Cancer can be identified by its symptoms at an early stage. There are many symptoms of cancer that are considered easily dismissible that can be caused by benign tumors, injury, illness, and other health issues.

The golden rule to raise an alarm concerning health is if a symptom is not getting better after a few days or weeks, then you should consult a doctor as soon as possible. This is the time to get diagnosed and treated timely if required.

The conventional treatment arms include cancer surgery, therapy, or any other treatment advised by the treating oncologist. Sometimes, you may not experience any kind of pain even if you have cancer as recommended by the clinical experience of the best oncologist in Gurgaon.

The idea is not to waste time waiting for symptoms to grow severe. Get in touch with a doctor at the earliest without underestimating the symptoms and don’t get afraid of the word cancer remember cancer is a group of diseases that is treatable.

A FEW SYMPTOMS THAT ARE ASSOCIATED WITH CANCER AND RAISE ALARM ARE:

1. Sudden Increase or Decrease in Body Weight – If you have increased or decreased your body weight but you do not know what the reason is, then you should consult your doctor and get diagnosed as soon as possible.

2. Lumps – Any unexplained lumps in your body could be a sign of cancer. A few body parts where you could find lumps are the groin area, testicles, stomach, underarms, or neck.

3. Swelling – If you are having any kind of swelling in any part of the body such as the groin, stomach, underarms, or neck, then get yourself checked by the doctor for cancer.

4. Changes in the Skin – says that it’s high time you get it checked by a doctor. Here are a few signs that you should look out for.

5. Yellow Skin & White in the Eyes – If you have yellow skin and white in the eyes, then you may have jaundice. Jaundice is one of the symptoms of cancer.

6. Non-Healing Soreness in your body – if it is not healing for a long time, then it might be a sign of cancer.

7. New Mole – If you recently have any new mole in your body or you can find any change in an already existing mole, then check yourself for the symptoms of cancer.

8. Bleeding – Bleeding or a Scaly Lump on the body, which is in flesh color and is bleeding or turning scaly, could be a symptom of cancer.

9. Neurological issues – Problems in Neurological Systems like face drooping, changes in hearing, changes in vision or eyesight, seizures, or headache, all these neurological symptoms could be a sign of cancer.

10. Changes of Mouth – Changes in the mouth such as numbness, pain, or bleeding in the mouth or lip, Red or white Patch in the mouth or on the tongue, Blood in saliva, and Night Sweating can be signs of underlying cancer.

11. Changes in Bowel habits – Abnormal bowel movements for a long time, it’s a cancer symptom that you need to watch out for. Pencil-thin stool or bloody stools are also cancer symptoms related to colon cancer.

12. Changes in the Bladder – It could be related to bladder cancer or pelvic tumor. These symptoms include blood in urine, pain while urinating, slow flow of urine, high-frequency urination, irritation, and a small amount of urine.

13. Changes in Breasts – It could be an indication of breast cancer. You can perform a self-examination and check for the signs: for instance, Puckered, dimpled, scaly, red, itchy breast skin, Discharge or changes in the nipple, Bloody discharge from the nipple, change in the size of breast or nipple, Breast feels different

In case you or your loved being is suspected of any above-mentioned signs or symptoms- consult your healthcare provider. The same is advocated by the best oncologists in a cancer hospital in Gurgaon, for early diagnosis of cancer.

And for a second opinion, you Can also consult the virtual hospital for cancer rounds.

Posted by, magneto

The Fourth Stanchion in The Treatment World of Cancer is Interventional Oncology- As Multidisciplinary Arm of Treatment

Interventional Oncology

One of the recent evolving branches of interventional radiology, which relies on highly sophisticated treatment tools accompanied by precise imaging guidance to target and destroy malignant tumors are referred to as Interventional Oncology.

The field of Interventional Oncology is an important pavement to potential benefits for both patients and the healthcare system.

Being a new discipline multidisciplinary treatment arm, interventional oncology is considered by the best hematologist in India as the wider field of oncology. In the cancer hospital Gurgaon, all oncologists, and experts prefer, its application in regard to a cornerstone of modern cancer care.

Yes, interventional oncology offers strong collaboration between radiation oncology and interventional oncology, aiming at treatment or cure means treatment with remission or palliative cure.

A robust quality-assurance framework to support the integration of interventional oncology into multidisciplinary care provides benefits to health care practitioners, cancer patients, and to the wider field of oncology research as well. A recent offshoot of interventional radiology is interventional oncology has evolved as an independent stanchion within multidisciplinary oncologic care.

Intervention oncology is one of the minimally-invasive image-guided tumor therapy defined as comprehensive unlimited technological innovation. Best hematologist in India and best oncologist in Mumbai refer patients for Interventional oncology with the expectation that minimally-invasive therapies incorporated in oncologic care plans with sister disciplines will gratify a new level of clinical collaboration. This is predicted to research results of many years and is more based on prospectively collected clinical evidence. An Interventional Oncology -IO practice is preferred in treatment regimen by a young generation that includes procedures like minimally-invasive, image-guided tumor therapies.

Workbench for an interventional oncologist incorporates less un-common services for cancer patients including venous/enteral access, biopsies, and palliative procedures. Mentioned cancer care tool kit is representing the initial point of contact. Followed by therapeutic concepts and rapid solutions for increasingly complex Carcinogenesis with symptom relief as a common result. The satisfaction rate in terms of patient analysis and quality care index pick a spike with an excellent impression of referring physicians and treating oncologists.

Cancer is now the leading cause of death worldwide and at the same time, medicine as a whole is undergoing a phase of transformation in the light turning to the dark of declining reimbursements. Recent advances have provided interventional oncology as a different treatment and the unique position of the treatment world of oncology. Being a technology-driven specialty, it is able to fulfil the professional requirements for highly specialized experts who have the skill and the will to grow a practice.

Maintaining and expanding the fourth stanchion of clinical oncology requires steps above the technical skills learned in a fellowship. For these interventional oncologists are ready to speak the language of oncology, which ensures broadening knowledge of the science and practice of interventional oncology.

Interventional oncology as a separate branch to communicate in oncology streams as a multidisciplinary arm focuses on the fundamentals of the other oncologic disciplines to be widely accepted treatment in guidelines for various cancers as well.

Our obligation of clinical research and development by Interventional Oncology upholds the rigid standards of evidence-based medicine and is surely an evolving oncological solution. Tremendous progress has been made over the last decade, to which an example is a trial involving the ability to influence clinical guidelines in lieu of hepatocellular carcinoma. In these two therapies performed by interventional oncologists, ablation and chemoembolization, are incorporated into official treatment guidelines globally. And new norm for answering clinical questions based on prospective multicentre phase II or III studies, either single-arm or randomized is on rapid research events.

To conclude Interventional Oncology is an exciting area which is exploiting vascular and non vascular procedures similar to or identical to other procedures performed by Interventional Radiologists. This allows oncologists in making practice development feasible to use physician extenders to maximize efficiency in practice.

Posted by, Medical Team, Cancer Rounds
January 18, 2022

BRCA1 and BRCA2: Potential Hereditary Breast Cancer Genes

Breast cancer

Yes, the most common cause of potential hereditary breast cancer is a mutation of the BRCA1 and BRCA2 genes. It is observed that these mutations can be inherited copies of either gene from a parent, and the individual is in the zone of a higher risk for breast cancer. In the physiological process, the mentioned BRCA1 AND BRCA2 genes make proteins to check and repair DNA. But on another side of the abnormal point when genes are mutated, can pose an abnormal cell growth or cancer.

Incidence of BRCA mutation: prevalence of pathogenic BRCA1 and BRCA2 variants has been reported- approximately 1 in 400 individuals in the general population. All individuals have BRCA1 and BRCA2 genes, but only some carry mutations in those genes. In case, either of the parents has a BRCA1 or BRCA2 gene mutation, offspring have a 50% chance of carrying the gene mutation. In genetic testing, BRCA positive mutation predicts risk of cancer increases and indicates a higher risk of developing breast cancer and ovarian cancer in women and the risk for breast and prostate cancer in men, as well as other cancers. If we are discussing epidemiology, it is a necessity to mention that a hereditary breast cancer accounts for only 5-10 percent of all breast cancers.

It is significant here to mention that females diagnose with either BRCA1 AND BRCA2 gene mutations are more likely to be diagnosed with breast cancer at a younger age. As we race to talk about genetic testing, the younger the age of diagnosis for BRCA positive mutation via genetic testing more appropriate the candidate is for BRCA1/2 pedigree. This pedigree unravels the classic features of the BRCA pathogenic variant across three generations. This will detail the result in organogram depicting/predicting affected family members with breast cancer and young age at onset

Location of BRCA1/2 and association with gender mutations & breast cancer: As per the data, the 17q21.3 region contained the BRCA1 gene and the BRCA2 gene is located on the 13q12.3 regions. Also, another fact as per the observational studies reported is that male breast cancer is unlikely to be directly caused by BRCA1 mutation alone.

BRCA 1/2 and tumorigenesis: recent data indicates that about 55 to 65% of BRCA1 mutation carriers and approximately 45% of BRCA2 mutation carriers develop breast cancer by 6 to 7 decades of life.

BRCA1 and BRCA2 are tumor suppressor genes, responsible to slow down cell division, repair DNA mistakes, or tell cells when to die in the physiological process. But in the mutation of the tumor suppressor gene or anti-oncogene, a loss or reduction in its function is base of tumorigeneses resulting in cancer.

Besides predicting the potential hereditary breast cancer recent ray of hope in breast cancer treatment regimen and follow-up is the role of BRCA mutations on breast cancer prognosis. As per data reported 3.4% BRCA carriers, display a not good overall survival. But collectively independent BRCA mutation is an inadequate outcome predictor.

It is because a clinical diagnosis of hereditary breast cancer also consider one or more of the features are present in family-like early-onset breast cancer, two breast primary or breast, and other related cancer (ovarian, fallopian tube, or primary peritoneal) in a single individual, and then a member of a family with a known BRCA1; etc.. in the recommended guidelines for genetic testing, counselling, and risk assessment. Which will be followed by primary prevention strategies to reduce breast cancer risk.

Breast cancer treatment in cases with BRCA1 or BRCA2 mutations: chemotherapy a conventional tool of treatment in the world of cancer uses Taxanes that are less sensitive to BRCA1 mutation carriers. Also, platinum agents with taxanes in neoadjuvant chemotherapy with enhanced response are predicted in hereditary BRCA1-associated breast cancer.

Targeted drug therapy- PARP inhibitors against BRCA1 or BRCA2 mutated genes are beneficial in the treatment of patients that are carriers of germline BRCA mutations.

The Breast cancer treatment cost in India typically is covered in the range from INR 5 to 6 Lakhs, including radiotherapy, surgery, testing, and targeted therapy spike the range up to 20 Lakh, including six cycles of chemotherapy for cancer treatment, genetic testing, genetic counseling, pedigree chart analysis. (For details please contact us)

Future considerations- In lieu of BRCA mutation will be able to provide valuable insight in terms of prevention and treatment options.

Posted by, Medical Team, Cancer Rounds
January 11, 2022

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