2nd

Feb 2022

Options to Preserve Fertility In Female Cancer Survivors

For cancer survivors to preserve fertility is the first physiological need these days. And fertility preservation thus is becoming increasingly significant to improve the quality of life in cancer survivors. The ability to have children is called fertility. Best hematologist in India and oncology team of the best cancer hospital in Gurgaon collectively advocate the recommended guidelines suggesting that discussion of fertility preservation should be done prior to starting cancer therapies.

Globally there is a lack of implementation in this area but India is leading with the solution as the oncologist team has session of counselling for patient in lieu of cryopreservation and fertility preservation.

To briefly introduce, with the research and innovations in the are there are number of techniques available for fertility preservation, and they can be used individually or together in the same patient to maximize efficiency.

Adding to this, Oocyte and embryo cryopreservation are now established techniques. The cryopreservations have their limitations but every lock has key. Ovarian tissue cryopreservation is a wider clinical application with the advantage of keeping the fertility window open for a longer time. Both the conventional arms of treatment, chemotherapy and radiotherapy have a major impact on reproductive potential. This is indicative of fertility preservation procedures – that should be carried out prior to these treatments.

Cancer in females of reproductive age accounts for nearly 10% of new cancer diagnoses. Most common cancers presenting in this group of youth affecting female include breast, thyroid, cervical, uterine, melanoma, lymphoma, and colon cancer. Over the past four decades, advances in surgery and adjuvant therapy have led to improved 5-year survival rates for breast (85.5%), endometrial (91%), cervical (83.2%), and ovarian cancers (79.5%). These improved outcomes have resulted in an increased number of cancer survivors but many therapies are harmful to the ovaries and put women at risk of premature ovarian failure and infertility. This is significant as nearly 25% of today’s cancer survivors are reproductive-aged woman who may wish to have children. Embryo cryopreservation is a widely established method for preserving reproductive capacity and due to its high pregnancy rates, it is considered the “gold standard” fertility preservation option. This procedure is offering the best chances of a live birth in the future as well. This solution also works in cases of male, that means the male cancer patient may store his sperm before treatment. Doing this is a way of preserving fertility.

But, in case you have undergone chemotherapy treatment then still no need to worry. After cancer treatment also, the ovarian tissue can be thawed and placed in the pelvis (transplanted). Once the transplanted tissue starts to function again, the eggs can be collected and attempts to fertilize them can be done in the lab. A man may have no sperm in his semen after cancer treatment. But he may still have healthy sperm in his testicles. During a testicular sperm extraction, the doctor removes small pieces of testicular tissue. Any healthy sperm cells found in this tissue can be used to make a baby.

The need for fertility preservation has not yet weighed against morbidity and mortality associated with cancer. Thus, a multidisciplinary collaboration between oncologists and reproductive specialists to improve awareness and availability is a necessity.

24th

Jan 2022

Chemotherapy for Prostate Cancer

As the name suggest Chemotherapy -chemo uses anti-cancer drugs. These drugs are injected into a vein or given by mouth. The chemo agents administered travel through the bloodstream to reach cancer cells in most parts of the body. Yes, in world of oncology chemotherapy is considered as conventional arm for treatment regimen.

It is essential here to consider that Chemotherapy is not only for killing cancer cells during treatment, while chemotherapy is also used in combination treatment therapy before radiation to shrink the lesion mass. In prostate cancer the role of chemotherapy is also important in cases when the cancer cells of prostate cancer have spread outside the prostate gland. Also, the effective role of chemotherapy is supported with data based and clinical evidence in treatment of prostate cancer when hormone therapy isn’t working.

As per recent research, the data is advocating that the chemotherapy is helpful in combination with hormone therapy- again this is option for some cases.

Yes, it is accepted fact that the chemotherapy alone is surely not considered a standard treatment for early prostate cancer.

The chemotherapeutic agents prescribed in treatment of prostate cancer:

Not: in diagnosis of prostate cancer the oncologist will administer the chemotherapy drugs one at a time, to the patient. Some of the chemo drugs used to treat prostate cancer include:

1. Docetaxel (Taxotere)

2. Cabazitaxel (Jevtana)

3. Mitoxantrone (Novantrone)

4. Estramustine (Emcyt)

Among the diagnosed cases of prostate cancer, many of the cases are being administered with the first drug given as docetaxel, which is combined with the steroid drug prednisone.

After the docetaxel that is in case when it does not work, cabazitaxel is often the next chemo drug tried.

As per the evidence-based data reported in literature the Docetaxel and are associated with increased disease-free survival rate. Both the mentioned drugs slow the cancer’s growth and also reduce symptoms, resulting in a better quality of life.

Other chemo drugs being studied for use in prostate cancer include:

1. Carboplatin

2. Oxaliplatin

3. Cisplatin.

Chemotherapy for prostate cancer is typically administered through a vein (IV). This can be achieved either as an infusion over a certain period of time. Some drugs given as pill are Estramustine.

For administering chemotherapy, slightly larger and sturdier IV is required. The IV administered for chemo patients are known as central venous catheters (CVCs), central venous access devices (CVADs), or central lines. Besides the administration of cancer treating medicines, they also help to administer blood products, nutrients, or fluids right into your blood and are also used to take out blood for testing.

Different kinds of CVCs available in the oncology hub; among which the most common types are the port and the PICC line.

Oncologist prefer administering chemotherapy through treatment regimen in cycles, and in each period or cycle of treatment followed by a rest period. This rest period is for patient, this rest time is for patients body to recover from the effects of the chemotherapy drugs. The chemotherapy cycles are most often 2 or 3 weeks long, and yes! the schedule varies depending on the drugs used.

In the prostate cancer during advanced stages, the length of chemotherapy treatment regimen is based on how well it is working, how patient’s body is responding and what side effects patients have.

For more details about Prostate cancer treatment in India, you can visit us at our website of CANCER ROUNDS. Our best oncologist’s team will counsel you and provide the innovations in prostate cancer treatment. On average the chemotherapy treatment cost in India is 70000/-INR.

It’s time to fight cancer without worrying about the cost as Cancer Rounds also guide and aid for funds to cancer patients.

10th

Jan 2022

OPTIMAL DIET FOR CANCER PATIENTS AND SURVIVORS- ANTI-INFLAMMATORY DIET

In the world of cancer, hematologist, oncologists focus on ways to reduce inflammation. The key to the lock lies not in the treatment regimen, but in the optimal diet.

Yes, the optimal diet for cancer patients and survivors is an anti-inflammatory diet. As it allows your body to fight off the inflammation that is able to damage your body’s healthy cells.

The mechanism of action by which an anti-inflammatory diet plan helps cancer patients and survivors:

First, let us discuss Inflammation: Biological immune response is activated when your body recognizes anything that is a foreign substance—such as an invading microbe, plant pollen, or chemical. This response triggers the cascade of inflammation. This natural process protects the human body as a defense but sometimes persisting inflammation even in absence of threatened foreign invaders is not normal.

Relating this most of the diseases/disorders including cancer, diabetes, arthritis, heart disease—have been linked to persistent or chronic inflammation.

And among the effective tools for battling chronic inflammation, comes from the grocery store.

Yes, in literature database trials and experimental studies have proven “components of nutrition with anti-inflammatory effects helps the body fight illness like cancer and can protect it from harm.

The anti-inflammatory diet- optimal diet for cancer patients and survivors includes prebiotics, fiber, omega-3s, and antioxidants.

Ideally, an optimal diet to fight inflammation in your body is required to be enriched with vegetables, fruits, grains, legumes, and/or fatty fish.

Best hematologists in India and best oncologists are always in favor of natural Anti-Inflammatories to be incorporated into the diet to fight against cancer or reduce the risk of cancer.

We know you are looking to understand more about natural anti-inflammatories but it may require changing your eating habits as well.

As during treatment of cancer, the role of medication along with other treatments are important, -similarly, an anti-inflammatory diet is a must. And same is foundation for designing diet plan for oncology patients at cancer hospital in Gurgaon.

Just! changing what’s on your plate is a miraculous cure as this lessens the number of flare-ups and lowers down a few notches of having other problems as well.

If you or your loved being is diagnosed with cancer – we suggest that the mainstream nutrition is to eat anti-inflammatory foods.

The next questions you might be worried about is –

How protein requirement of the body will be fulfilled? – The quick fix to this is plant-based proteins (like beans and nuts).

The main outlook in an optimal diet plan for the anti-inflammatory diet of cancer patients or survivors is to avoid highly processed, overly greasy, or super sweet food.

Our specialized team of well-known and best oncologist, hematologist hereby support optimal diet/ anti-inflammatory meal plan helping to keep inflammation under control.

Anti-inflammatory recipes that can help you to make an optimal diet plan delicious are mentioned here:

Oat porridge garnished with berries is a tasty meal to start a day that assure high doses of prebiotics, antioxidants, and fiber.
For gluten-free options we can opt buckwheat and chia seed porridge. It will be able to boost omega-3 content, fiber, and protein.
Turmeric in Scrambled eggs is surely an excellent source of protein, and vitamin D- with an extra anti-inflammatory boost. Since, Turmeric is rich in a compound called curcumin, responsible for managing oxidative and inflammatory conditions.
Pineapple smoothie- another kick to start a day that is full of fiber and protein. The high levels of bromelain, which has anti-inflammatory is in Pineapple.
Spinach tortilla that may be accompanied with a salad of green leafy vegetables, and broccoli, is a rich source of two polyphenols called quercetin and coenzyme Q10 and this reduces inflammation.
Quinoa and citrus fruit salad contain lots of protein and nutrients with an antioxidant boost.
Grape and apple slaw is a fun side dish that is a good source of another anti-inflammatory polyphenol called anthocyanins, resveratrol that helps to reduce inflammation.

We mention here that ingredients in food provide healthful benefits, but it’s still very essential to include a wide variety of whole food in the diet. The idea of the optimal diet with anti-inflammatory properties is to maintain balance.

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