Cyclophosphamide – Uses, Side Effects and Precautions



Cyclophosphamide is a chemotherapy medication that is used to treat cancer. It works by inhibiting the growth and division of cancer cells, which can help to slow or stop the spread of cancer in the body. Cyclophosphamide is typically administered intravenously (through a vein) or orally (by mouth). 

Cyclophosphamide can be used to treat a variety of different types of cancer, including breast cancer, ovarian cancer, lymphoma, and leukemia. It is often used in combination with other chemotherapy medications and may be given as part of a treatment plan that includes surgery and/or radiation therapy. 

Like all chemotherapy medications, cyclophosphamide can cause side effects, including nausea, vomiting, diarrhea, hair loss, and an increased risk of infection. These side effects can be managed with medications and other supportive care measures. It is important to discuss the potential risks and benefits of cyclophosphamide treatment with a healthcare provider before starting treatment. 


What cancers does cyclophosphamide treat? 

Cyclophosphamide is used to treat several different types of cancers which majorly include blood cancer and some gynecological cancers. It stops the growth of cancer cells in the body of the patients. The doctor can use the drug for the treatment of other diseases if they think it can cure it. The nephrotic syndrome also gets treated with the help of cyclophosphamide.  

Cyclophosphamide is often used to treat: 


How is it given? 

Cyclophosphamide is usually given as an injection into a vein (intravenous, or IV) or as a pill. 

If you are receiving cyclophosphamide as an IV injection, the drug will be given through a needle or catheter inserted into a vein in your arm, hand, or chest. The injection typically takes 15-30 minutes to administer. 

If you are taking cyclophosphamide as a pill, you will swallow it with a glass of water. The dose and frequency of cyclophosphamide pills will depend on your specific treatment plan. 

It’s important to follow your doctor’s instructions carefully when taking cyclophosphamide. You may be asked to drink plenty of fluids and urinate frequently to help flush the drug out of your body. 


Send Enquiry


What are the common side effects of cyclophosphamide? 

Like any other chemotherapy drug, cyclophosphamide also causes some side effects that can be managed through certain precautions and lifestyle changes. You may also be given medications to help prevent side effects and control any major complications. Some of the major side effects of cyclophosphamide that affect the patients are as follows: 

  • Nausea 
  • Vomiting 
  • Loss of appetite  
  • Weight loss 
  • Abdominal pain 
  • Diarrhea 
  • Hair loss 
  • Mouth soreness 
  • Changes in skin color 
  • Changes in color or growth of finger or toenails 
  • Swelling 
  • Chest pain 
  • Rashes 
  • Fever and chills 
  • Cough 
  • Shortness of breath 

If these symptoms get worse, then you should either contact your doctor or visit the hospital as soon as possible.  


What are the precautions you should take? 

Chemotherapy drugs are used to treat cancer while killing the cancerous cells in the body of the patient. While it can be an effective cancer treatment, it can also have several side effects. To help minimize these side effects and stay as healthy as possible during chemotherapy, there are a few precautions you can take: 

  1. Consult your doctor before taking any nutritional supplements, herbal supplements, or any other prescription drugs. Avoid taking any over-the counter- drugs as they can interact with cyclophosphamide and hinders its function. 

  2. Chemotherapy drugs like cyclophosphamide can cause dehydration, so it’s important to drink plenty of fluids. Aim for at least 8 cups of water or other non-alcoholic beverages daily. 

  3. It is advised to choose high-protein and energy food. Chemo drugs can cause appetite changes, but it’s important to try to eat a healthy, balanced diet. Choose foods that are high in protein, fiber, and nutrients to help you maintain your strength and energy. 

  4. Cancer treatment can be physically and emotionally draining, so it’s important to get plenty of rest. Make sure to get enough sleep at night and take breaks during the day if you need to. 

  5. To help prevent infection, wash your hands frequently and avoid close contact with people who are sick. 

  6. While taking any chemotherapy drugs it is advised to not get pregnant or breastfeed an infant. It can be harmful to the infant. 


If you have any concerns or questions about your chemotherapy treatment, don’t hesitate to talk to your doctor or nurse. They can provide you with more information and help you manage any side effects you may be experiencing. 


Send Enquiry

Contact Us

    Mobile Number